The GRANDIOSA study (‘GRowth, Allergy and NeuroDevelopment in Infants On hydrolySed formulA’) started in 2022 and is conducted in Umeå and Malmö.
The purpose of the study is to determine the effects of two novel protein hydrolysates on infants’ growth, neurological development, allergies, gastrointestinal symptoms and other health outcomes. GRANDIOSA is a blinded, placebo-controlled, randomized clinical trial to test two new partially hydrolysed infant formulas. The children will follow their assigned regimen until they are five months old and there are regular follow-ups.
There is a dedicated website (in Swedish); https://www.grandiosastudien.se/
Digital meetings are held quarterly and previous IRL meetings took place on 20 Oct 2023 in Umeå and 8 Nov 2024 in Malmö. Now it was time for the sponsor Arla Foods Ingredients to host, and the meeting was held in Aarhus, Denmark on Friday 3 October 2025.
Participants at the meeting were:
From Umeå: Magnus Domellöf (PI), Christina West (co-PI), Sara Olivecrona (PhD student), Gunilla Strinnholm and Marie Lindvall (research nurses)
From Malmö: Pia Karlsland Åkeson (PI), Ingrid Avenäs and Filippa Wikström (research nurses).
PhD student Eleni Kordi was unable to attend.
From Arla Foods Ingredients: Lotte Neergaard Jacobsen and Anne Staudt Kvistgaard
The morning had a number of presentations from Arla as well as updates on the study recruitment, response from parents etc. There was also a discussion where it was decided to try to get funding for a 3-year follow-up. After lunch the team received a presentation on the services provided by Arla Foods Ingredients and information on regulatory approval of hydrolysates and there was a discussion on the planned publications.
After the meeting there was also time for a visit to the art museum Aros.
“This was a very rewarding meeting, the study is progressing according to plan, and it seems we will be able to finalize recruitment in a little more than a year from now” said Magnus Domellöf, PI for the study in Umeå.
Meeting participants from left to right in the photo above: Gunilla, Marie, Ingrid, Magnus, Pia, Christina, Sara, Filippa, Anne and Lotte